Área de interés/experiencia en investigación

• Síntesis, caracterización y evaluación de materiales poliméricos del tipo dendrímero funcionalizados con fármacos para su aplicación en nanomedicina.
• Desarrollo de organocatalizadores quirales y su evaluación en reacciones de síntesis asimétrica.
• Catálisis heterogénea con aplicación en síntesis de química fina.
• Desarrollo de metodologías no convencionales en condiciones de química verde para la síntesis de moléculas orgánicas de alto valor agregado

Publicaciones en Revistas

José M. Landeros, Hugo A. Silvestre, Patricia Guadarrama, “Synthesis of branched cores by poly-O-alkylation reaction under phase transfer conditions. A systematic study“, Journal of Molecular Structure, 1037, 412-419, 2013. DOI: 10.1016/j.molstruc.2013.01.034

José M. Landeros, Fernando Belmont-Bernal, Alma T. Pérez-González, Mario I. Pérez-Padrón, Patricia Guevara-Salazar, Irma G. González-Herrera, Patricia Guadarrama, “A two-step synthetic strategy to obtain a water-soluble derivative of curcumin with improved antioxidant capacity and in vitro cytotoxicity in C6 glioma cells”, J. Mater. Sci. Eng. C, 2017, 71, 351–362. DOI: 10.1016/j.msec.2016.10.015

José M. Landeros, Eusebio Juaristi. Mechanochemical Synthesis of Dipeptides Using Mg-Al Hydrotalcite as Activating Agent under Solvent-Free Reaction Conditions. European Journal of Organic Chemistry, 2017, 3, 687–694. DOI: 10.1002/ejoc.201601276

José M. Landeros, Lydia Suchy, Claudia G. Ávila-Ortiz, Nuno Maulide, Eusebio Juaristi. Dendrimeric α,β-dipeptidic conjugates as organocatalysts in the asymmetric Michael addition reaction of isobutyraldehyde to N-phenylmaleimides, Monatsh. Chem., 2019, 150, 777-788, DOI: 10.1007/s00706-018-2338-0

Carlos Cruz-Hernández, José M. Landeros, Eusebio Juaristi. Multifunctional Phosphoramide-(S)-Prolinamide Derivatives as Efficient Organocatalysts in Asymmetric Aldol and Michael Reactions. New Journal of Chemistry, 2019, 43, 5455-5465. DOI: 10.1039/C9NJ00300B

José M. Landeros, Carlos Cruz-Hernández, Eusebio Juaristi, α-Amino Acids and α,β-Dipeptides Intercalated into Hydrotalcite: Efficient Catalysts in the Asymmetric Michael Addition Reaction of Aldehydes to N-Substituted Maleimides European Journal of Organic Chemistry, 2021, 37, 5117–5126. DOI: 10.1002/ejoc.202100877

Memorias de Congreso

J. M. Landeros, P. Guadarrama, “Soluble Dendrimer Based on Bis-MPA and 1,1,1-Tris(hydroximethyl) ethane Bearing Methotrexate Drug”, International Conference on Polymers and Advanced Materials (POLYMAT), 2011, Huatulco, México.

J. Landeros, L. Lomas, R. Gaviño, J. Cárdenas, and G. Negrón, “Mild and solvent free eficiente silylcyanation of pentacyclo [5.4.0.0^2,6.0^3,10.0^5,9]undecane-8,11-dione catalyzed by hydrotalcite”. 16 th International Conference in Organic Synthesis, 2006. Mérida, México.

J. M. Landeros, P. Guadarrama "Synthesis and biological evaluation of dendrimers polyester type containing methotrexate drugs". XXI International Materials Research Congress. 2012, Cancún, México.

J. M. Landeros, Patricia Guadarrama, Poster: “Dendrímeros solubles en agua derivados del 1,1,1-tris(hidroximetil)etano y bis-MPA como acarreador de metotrexato”. Segundo Congreso de Posgrado de la UNAM, 2012. D.F., México.

J. M. Landeros, F. Belmont-Bernal, M. Maya-López, I. G. González-Herrera, P. Guadarrama, “Synthesis of Dendron-Curcumin conjugates and their evaluation of anti-oxidant response”. International Conference on Polymers and Advanced Materials, “POLYMAT”/Simposio Latinoamericano de Química de Coordinación y Organometálica “SILQCOM”. 2013. Huatulco, México.